Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 2/20 | 0.59 |
| ▸ | CACNA1F | O60840 | 10/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 10/20 | 0.49 |
| ▸ | CACNA1S | Q13698 | 10/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 10/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732316 | 0.93 | CACNA1F (0.55) | NR3C2CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL9732409 | 0.86 | CACNA1F (0.64) | NR3C2CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL9732179 | 0.84 | CACNA1F (0.63) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL9732705 | 0.84 | CACNA1C (0.55) | NR3C2CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL3034907 | 0.82 | NR3C2 (0.61) | NR3C2CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL3026973 | 0.82 | NR3C2 (0.61) | NR3C2CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL3018702 | 0.82 | NR3C2 (0.61) | NR3C2 | |
| SCHEMBL9734452 | 0.81 | CACNA1F (0.59) | NR3C2CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL3022593 | 0.81 | ADORA3 (0.59) | NR3C2CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL6951602 | 0.81 | CACNA1C (0.63) | NR3C2CACNA1FCACNA1DCACNA1SCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158963-A | Cognition activators; improve brain function | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1992-10-27 | — | — | US | disclosed |
| EP-0411549-A1 | 1,4-dihydropyridine derivative, process for preparing the same and pharmaceutical composition containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1991-02-06 | — | — | EP | disclosed |