Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 6/20 | 0.36 |
| ▸ | OPRK1 known ✓ | P41145 | 5/20 | 0.36 |
| ▸ | PLG | P00747 | 6/20 | 0.39 |
| ▸ | PLAT | P00750 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 8/20 | 0.39 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | NRP1 | O14786 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL9733269 | 0.92 | F2 (0.40) | PLGPLATF2F10PRSS1 | |
| Sulfuric Acid SCHEMBL9733510 | 0.91 | F2 (0.39) | PLGPLATF2F10PRSS1 | |
| Sulfuric Acid SCHEMBL27533420 | 0.89 | PLG (0.42) | PLGPLATF2F10PRSS1 | |
| Sulfuric Acid SCHEMBL10456107 | 0.89 | PLG (0.42) | PLGPLATF2F10PRSS1 | |
| Sulfuric Acid SCHEMBL9733730 | 0.87 | DPP4 (0.47) | PLGF2F10PRSS1NTSR2 | |
| Sulfuric Acid SCHEMBL9733221 | 0.86 | DPP4 (0.45) | PLGF2F10PRSS1OPRM1 | |
| Sulfuric Acid SCHEMBL9618234 | 0.86 | CAPN1 (0.40) | PLGF2F10PRSS1NTSR2 | |
| Sulfuric Acid SCHEMBL7264620 | 0.85 | F2 (0.54) | PLGF2OPRM1OPRK1 | |
| Sulfuric Acid SCHEMBL9733332 | 0.85 | F2 (0.47) | PLGF2F10PRSS1OPRM1 | |
| SCHEMBL27553573 | 0.85 | PLG (0.44) | PLGPLATF2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153176-A | Substituted lysine-proline-arginine peptide | NITTO BOSEKI CO., LTD. (JP) | 1992-10-06 | — | — | US | disclosed |