Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 7/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731797 | 0.94 | ALDH1A1 (0.52) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9731616 | 0.94 | TOP2A (0.53) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9732145 | 0.84 | PIM1 (0.54) | ALDH1A1POLBKDM4EHPGDHSD17B10 | |
| SCHEMBL9731260 | 0.82 | TOP2A (0.55) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9732961 | 0.82 | ALDH1A1 (0.55) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9732627 | 0.81 | TOP2A (0.52) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9383693 | 0.81 | TOP2A (0.69) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9732003 | 0.80 | TOP2A (0.49) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9731714 | 0.80 | ALDH1A1 (0.53) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9731431 | 0.80 | TOP2A (0.48) | ALDH1A1POLBOPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081254-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| US-4929613-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0306764-A2 | 4-Quinolone-3-carboxylic-acid derivatives and their use as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-03-15 | — | — | EP | disclosed |