Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731919 | 0.95 | LMNA (0.55) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9731667 | 0.87 | LMNA (0.53) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9731522 | 0.84 | LMNA (0.51) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9732019 | 0.83 | KDM4E (0.52) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9731768 | 0.83 | LMNA (0.55) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9731393 | 0.83 | LMNA (0.62) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9731087 | 0.82 | LMNA (0.69) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9731957 | 0.81 | LMNA (0.59) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9733323 | 0.81 | PIM1 (0.51) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL10578012 | 0.81 | LMNA (0.53) | LMNAKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081254-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| US-4929613-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0306764-A2 | 4-Quinolone-3-carboxylic-acid derivatives and their use as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-03-15 | — | — | EP | disclosed |