Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 2/20 | 0.32 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397107 | 0.80 | TSHR (0.47) | TSHRCYP2C19TGM2 | |
| SCHEMBL3107212 | 0.80 | TSHR (0.43) | TSHRCYP2C19TGM2 | |
| SCHEMBL19146552 | 0.78 | TSHR (0.44) | TSHRTGM2ACACB | |
| SCHEMBL20081800 | 0.71 | TSHR (0.48) | TSHRCYP2C19TEAD1ACACB | |
| SCHEMBL1070614 | 0.70 | TSHR (0.47) | TSHR | |
| SCHEMBL730166 | 0.70 | TSHR (0.47) | TSHRCYP2C19TGM2TEAD1 | |
| SCHEMBL636063 | 0.67 | TSHR (0.71) | TSHRCYP2C19TGM2ACACB | |
| SCHEMBL22847916 | 0.67 | TSHR (0.47) | TSHRTEAD1 | |
| SCHEMBL26479936 | 0.67 | TSHR (0.71) | TSHRCYP2C19TGM2ACACB | |
| SCHEMBL27799665 | 0.67 | TSHR (1.00) | TSHRCYP2C19TGM2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399530-B2 | Polymer foams | BASF SE (DE) | 2013-03-19 | — | — | US | disclosed |
| US-20110015288-A1 | POLYMER FOAMS | BASF SE (DE) | 2011-01-20 | — | — | US | disclosed |