⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48036 | 0.78 | — | — | |
| Methyl Alcohol SCHEMBL9770976 | 0.75 | ALDH1A1 (0.37) | — | |
| SCHEMBL8631505 | 0.75 | — | — | |
| SCHEMBL10709840 | 0.75 | — | — | |
| SCHEMBL11439849 | 0.73 | ALDH1A1 (0.41) | — | |
| SCHEMBL1056782 | 0.73 | — | — | |
| Methyl Alcohol SCHEMBL10802034 | 0.73 | HMGCR (0.52) | — | |
| Methylene Chloride SCHEMBL1249909 | 0.73 | ALDH1A1 (0.35) | — | |
| Methylene Chloride SCHEMBL9688806 | 0.73 | ALDH1A1 (0.35) | — | |
| SCHEMBL11880618 | 0.73 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621094-B | Compound with islet protection function and preparation method and application thereof | 海南医学院 | 2023-02-10 | — | — | CN | claimed |
| CN-114621094-A | Compound with islet protection function and preparation method and application thereof | 海南医学院 | 2022-06-14 | — | — | CN | claimed |
| CN-111617154-B | Preparation method and application of anti-islet cell apoptosis comfrey extract | 海南医学院 | 2022-02-22 | — | — | CN | claimed |
| CN-111617154-A | Preparation method and application of anti-islet cell apoptosis comfrey extract | 海南医学院 | 2020-09-04 | — | — | CN | claimed |
| CN-115925728-B | Preparation method and application of near infrared probe for kidney injury diagnosis | 南京林业大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-114621094-B | Compound with islet protection function and preparation method and application thereof | 海南医学院 | 2023-02-10 | — | — | CN | disclosed |
| CN-114621094-A | Compound with islet protection function and preparation method and application thereof | 海南医学院 | 2022-06-14 | — | — | CN | disclosed |
| CN-111617154-B | Preparation method and application of anti-islet cell apoptosis comfrey extract | 海南医学院 | 2022-02-22 | — | — | CN | disclosed |
| CN-111617154-A | Preparation method and application of anti-islet cell apoptosis comfrey extract | 海南医学院 | 2020-09-04 | — | — | CN | disclosed |
| CN-106749107-A | Terpenoid in Roots of Euphorbia soongarica and its production and use | 中国科学院新疆理化技术研究所 | 2017-05-31 | — | — | CN | disclosed |
| US-5138067-A | PAF antagonists, antithrombotic, antivasoconstricting, antibronchoconstricting or antitumor agents | SHIONOGI & CO. LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| CN-1054601-A | Azabicyclo and azepine cyclic oximes and amine cholinergic agents thing and methods of treatment thereof | WARNER LAMBERT CO (US) | 1991-09-18 | — | — | CN | disclosed |
| US-5047540-A | Platelet Activating Factor Antagonists and Antitumor Agents | SHIONOGI & CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| US-4219489-A | Synthesis of steroids | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1980-08-26 | — | — | US | disclosed |
| US-4198420-A | Spiro[dibenz(b,f)thiepin-piperidine]s | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |
| US-4198418-A | ANALGESICS, TRANQUILIZERS, ANTICONVULSANTS | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |