Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SMO | Q99835 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13585606 | 0.83 | GAA (0.50) | MGLLMEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL13879504 | 0.77 | ELANE (0.47) | ELANEMGLLMEN1KMT2AHSD17B10 | |
| SCHEMBL13879522 | 0.73 | LMNA (0.62) | ELANEMGLLMEN1KMT2AHSD17B10 | |
| SCHEMBL13879428 | 0.71 | LMNA (0.49) | ELANEMGLLMEN1KMT2AHSD17B10 | |
| SCHEMBL13879419 | 0.70 | AR (0.62) | ELANEMGLLMEN1KMT2AALDH1A1 | |
| SCHEMBL11866914 | 0.69 | LMNA (0.47) | ELANEMGLLMEN1KMT2AHSD17B10 | |
| SCHEMBL13879400 | 0.69 | GRM2 (0.44) | ELANEMGLLALDH1A1SMOLMNA | |
| SCHEMBL11612591 | 0.68 | KMT2A (0.48) | ELANEMGLLMEN1KMT2AALDH1A1 | |
| SCHEMBL4437165 | 0.67 | LMNA (0.54) | MGLLMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4439021 | 0.67 | LMNA (0.54) | MGLLMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098888-A | Cholinergic agents and antispasmodic agents | ADIR ET COMPAGNIE (FR) | 1992-03-24 | — | — | US | disclosed |
| EP-0105102-A1 | 2-Aza-bicyclo(2,2,2)-octane-3-carboxylic-acid derivatives, process for their preparation, pharmaceutical preparations containing them and their application, and 2-aza-bicyclo(2,2,2)-octane-3-carboxylic acid as an intermediate and its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-04-11 | — | — | EP | disclosed |