Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732573 | 0.95 | PIM1 (0.54) | PIM1ALDH1A1KDM4EPOLBHSP90AA1 | |
| SCHEMBL9731630 | 0.86 | KCNH2 (0.48) | ALDH1A1KDM4EPOLBLMNAHPGD | |
| SCHEMBL9730689 | 0.86 | PIM1 (0.51) | PIM1ALDH1A1KDM4EPOLBHSP90AA1 | |
| SCHEMBL9733323 | 0.85 | PIM1 (0.51) | PIM1ALDH1A1KDM4EPOLBHSP90AA1 | |
| SCHEMBL9731522 | 0.83 | LMNA (0.51) | PIM1ALDH1A1KDM4EPOLBHSP90AA1 | |
| SCHEMBL9731403 | 0.82 | PIM1 (0.53) | PIM1ALDH1A1KDM4EPOLBHSP90AA1 | |
| SCHEMBL9732888 | 0.81 | PIM1 (0.52) | PIM1ALDH1A1KDM4EPOLBHSP90AA1 | |
| SCHEMBL9730945 | 0.81 | PIM1 (0.52) | PIM1ALDH1A1KDM4EPOLBHSP90AA1 | |
| SCHEMBL9733155 | 0.81 | KCNH2 (0.49) | ALDH1A1KDM4EPOLBLMNAHPGD | |
| SCHEMBL9732912 | 0.80 | LMNA (0.55) | PIM1ALDH1A1KDM4EPOLBHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081254-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| US-4929613-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0306764-A2 | 4-Quinolone-3-carboxylic-acid derivatives and their use as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-03-15 | — | — | EP | disclosed |