Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 18/20 | 0.82 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733134 | 0.90 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL9733060 | 0.90 | TBXAS1 (0.85) | TBXAS1TBXA2R | |
| SCHEMBL9733030 | 0.86 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL9734468 | 0.86 | TBXAS1 (0.82) | TBXAS1TBXA2R | |
| SCHEMBL9733047 | 0.85 | TBXAS1 (0.75) | TBXAS1TBXA2RALDH1A1IDO1 | |
| SCHEMBL9732621 | 0.85 | TBXAS1 (0.81) | TBXAS1TBXA2RIDO1 | |
| SCHEMBL9733526 | 0.84 | TBXAS1 (0.67) | TBXAS1TBXA2R | |
| SCHEMBL9732154 | 0.84 | TBXAS1 (0.82) | TBXAS1TBXA2R | |
| SCHEMBL9734224 | 0.81 | TBXAS1 (0.75) | TBXAS1TBXA2RIDO1 | |
| SCHEMBL9732992 | 0.79 | TBXAS1 (0.85) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153214-A | Treating cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-5025025-A | Cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1991-06-18 | — | — | US | disclosed |
| EP-0405391-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | disclosed |