Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2295601 | 0.81 | NPC1 (0.69) | ALDH1A1TAAR1NPC1HSD17B10RECQL | |
| SCHEMBL18833849 | 0.81 | NPC1 (0.49) | ALDH1A1NPC1CA12CA1CA2 | |
| SCHEMBL6693064 | 0.81 | NPC1 (0.69) | ALDH1A1TAAR1NPC1HSD17B10RECQL | |
| SCHEMBL2294626 | 0.81 | NPC1 (0.69) | ALDH1A1TAAR1NPC1HSD17B10RECQL | |
| SCHEMBL28302031 | 0.80 | NPC1 (0.73) | ALDH1A1NPC1MAPTGAAL3MBTL1 | |
| SCHEMBL16806070 | 0.80 | ALDH1A1 (0.49) | ALDH1A1NPC1CA12CA1CA2 | |
| SCHEMBL28302029 | 0.80 | NPC1 (0.73) | ALDH1A1NPC1MAPTGAAL3MBTL1 | |
| SCHEMBL28934149 | 0.80 | NPC1 (0.73) | ALDH1A1NPC1MAPTGAAL3MBTL1 | |
| SCHEMBL16806068 | 0.80 | ALDH1A1 (0.49) | ALDH1A1NPC1CA12CA1CA2 | |
| SCHEMBL16806066 | 0.79 | ALDH1A1 (0.50) | ALDH1A1NPC1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079248-A | Antifibrillatory agents; side effect reduction | PFIZER INC. (US) | 1992-01-07 | — | — | US | disclosed |
| US-4959366-A | Anti-arrhythmic agents | PFIZER INC. (US) | 1990-09-25 | — | — | US | disclosed |