Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.58 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.58 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733910 | 1.00 | PARP10 (0.58) | PARP10PARP15PARP2HPGDMEN1 | |
| SCHEMBL154421 | 0.86 | PARP10 (0.57) | PARP10PARP15PARP2HPGDMEN1 | |
| SCHEMBL9636658 | 0.86 | PARP10 (0.57) | PARP10PARP15PARP2HPGDMEN1 | |
| SCHEMBL9734423 | 0.85 | PARP10 (0.53) | PARP10PARP15PARP2HPGDMEN1 | |
| SCHEMBL9734420 | 0.85 | PARP10 (0.53) | PARP10PARP15PARP2HPGDMEN1 | |
| SCHEMBL10426427 | 0.83 | PARP15 (0.53) | PARP10PARP15PARP2HPGDRAB9A | |
| SCHEMBL10426426 | 0.83 | PARP15 (0.53) | PARP10PARP15PARP2HPGDRAB9A | |
| SCHEMBL20024716 | 0.82 | HPGD (0.58) | PARP10PARP15PARP2HPGDTLR4 | |
| SCHEMBL23866742 | 0.80 | MAOB (0.59) | KMT2ANPC1POLBRAB9A | |
| SCHEMBL8007805 | 0.78 | GSK3B (0.64) | HPGDMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135955-A | Anticoagulants or antifungal activity | ELI LILLY AND COMPANY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0339878-A2 | Propanamine derivatives | ELI LILLY AND COMPANY (US) | 1989-11-02 | — | — | EP | disclosed |