Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.57 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.52 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154421 | 1.00 | PARP10 (0.57) | PARP10PARP15HPGDRARBPARP2 | |
| SCHEMBL8377643 | 0.90 | PARP15 (0.48) | PARP10PARP15HPGDRARBPARP2 | |
| SCHEMBL9733910 | 0.86 | PARP10 (0.58) | PARP10PARP15HPGDPARP2MEN1 | |
| SCHEMBL28372609 | 0.86 | THRB (0.48) | PARP10PARP15PARP2NPC1RAB9A | |
| SCHEMBL3357904 | 0.86 | HPGD (0.54) | PARP10PARP15HPGDPARP2NPC1 | |
| SCHEMBL3361329 | 0.86 | THRB (0.51) | PARP10PARP15HPGDPARP2MEN1 | |
| SCHEMBL3357907 | 0.86 | HPGD (0.54) | PARP10PARP15HPGDPARP2NPC1 | |
| SCHEMBL9733911 | 0.86 | PARP10 (0.58) | PARP10PARP15HPGDPARP2MEN1 | |
| SCHEMBL3361322 | 0.86 | THRB (0.51) | PARP10PARP15HPGDPARP2MEN1 | |
| SCHEMBL10426427 | 0.85 | PARP15 (0.53) | PARP10PARP15HPGDPARP2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315913-B1 | ANTISEBORRHOIC TOPICAL COMPOSITIONS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1992-06-10 | — | — | EP | disclosed |
| US-4939171-A | Alkyl and alkenyl aryl ether derivatives; cosmetics | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1990-07-03 | — | — | US | disclosed |
| EP-0315913-A1 | Antiseborrhoic topical compositions | Henkel Kommanditgesellschaft auf Aktien (DE) | 1989-05-17 | — | — | EP | disclosed |