Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | FBP1 | P09467 | 9/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6098151 | 0.82 | KMT2A (0.52) | KMT2AFBP1MMP2MEN1NLRP3 | |
| SCHEMBL13656915 | 0.80 | KMT2A (0.50) | KMT2AFBP1MMP2MEN1NLRP3 | |
| SCHEMBL751112 | 0.80 | KMT2A (0.50) | KMT2AFBP1MMP2MEN1NLRP3 | |
| SCHEMBL10765775 | 0.78 | KMT2A (0.49) | KMT2AFBP1MMP2MEN1NLRP3 | |
| SCHEMBL26489351 | 0.77 | KMT2A (0.47) | KMT2AMEN1L3MBTL1ACHEKDM4E | |
| SCHEMBL30387998 | 0.77 | KMT2A (0.55) | KMT2AFBP1MMP2MEN1ACHE | |
| SCHEMBL4619061 | 0.77 | KMT2A (0.55) | KMT2AFBP1MMP2MEN1ACHE | |
| SCHEMBL822302 | 0.76 | KMT2A (0.59) | KMT2AFBP1MMP2MEN1L3MBTL1 | |
| SCHEMBL29468572 | 0.76 | KMT2A (0.59) | KMT2AFBP1MMP2MEN1L3MBTL1 | |
| SCHEMBL31263633 | 0.76 | LMNA (0.61) | KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175302-A | Nucleophilic fluoroalkylation of aldehydes | ETHYL CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| US-4999429-A | Process for the preparation of α,α,β-1-trifluoro-1-olefinic derivatives | ETHYL CORPORATION (US) | 1991-03-12 | — | — | US | disclosed |
| US-4837327-A | Process for nucleophilic fluoroalkylation of aldehydes | ETHYL CORPORATION (US) | 1989-06-06 | — | — | US | disclosed |