Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 6/20 | 0.59 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CLK2 | P49760 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9147834 | 0.91 | TOP2A (0.58) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL9147827 | 0.91 | TOP2A (0.58) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL9147844 | 0.91 | TOP2A (0.58) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL9146215 | 0.84 | ALDH1A1 (0.59) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL9149682 | 0.84 | ALDH1A1 (0.59) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL9150515 | 0.84 | ALDH1A1 (0.59) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL9146205 | 0.84 | ALDH1A1 (0.59) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL9146224 | 0.84 | ALDH1A1 (0.59) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL9671100 | 0.83 | TOP2A (0.59) | TOP2ATOP2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL9177373 | 0.83 | TOP2A (0.52) | TOP2ATOP2BKCNH2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153204-A | Bactericides, animal growth promoters | BAYER AKTIENGESELLSCHAFT (DE) | 1992-10-06 | — | — | US | claimed |