Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214363 | 0.87 | CCR1 (0.50) | CCR1PIN1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL2516644 | 0.86 | MAPT (0.41) | CCR1SMN1; SMN2POLBNPSR1ALDH1A1 | |
| SCHEMBL1625711 | 0.85 | CCR1 (0.48) | CCR1PIN1POLBTDP1NPSR1 | |
| SCHEMBL27450756 | 0.84 | CCR1 (0.48) | CCR1PIN1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL9734250 | 0.84 | CCR1 (0.54) | CCR1PIN1SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL8311559 | 0.82 | OPRM1 (0.49) | SMN1; SMN2POLBHSD11B1TDP1TSHR | |
| SCHEMBL22323105 | 0.82 | CCR1 (0.54) | CCR1PIN1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL2636117 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBHSD11B1TDP1PPID | |
| SCHEMBL22323061 | 0.81 | CCR1 (0.46) | CCR1PIN1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL18153522 | 0.80 | SMN1; SMN2 (0.48) | CCR1SMN1; SMN2POLBNPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164386-A | Gastrointestinal and respiratory disorders | ISTITUTO DE ANGELI S.P.A. (IT) | 1992-11-17 | — | — | US | disclosed |
| EP-0404737-A2 | New R(-) 3-quinuclidinol derivatives | BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) | 1990-12-27 | — | — | EP | disclosed |