SCHEMBL9734637

SCHEMBL9734637

O[C@]1(c2ccc(Cl)s2)CCCC[C@H]1n1cncn1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.30
TDO2 P48775 4/20 0.30
CYP17A1 P05093 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9734640 1.00 IDO1 (0.30) IDO1TDO2CYP17A1
SCHEMBL9736581 1.00 IDO1 (0.30) IDO1TDO2CYP17A1
SCHEMBL9734636 1.00 IDO1 (0.30) IDO1TDO2CYP17A1
SCHEMBL9736578 1.00 IDO1 (0.30) IDO1TDO2CYP17A1
SCHEMBL9733890 0.99 IDO1 (0.32) IDO1TDO2CYP17A1
SCHEMBL9733883 0.99 IDO1 (0.32) IDO1TDO2CYP17A1
SCHEMBL9733887 0.99 IDO1 (0.32) IDO1TDO2CYP17A1
SCHEMBL9734681 0.79 CHRM3 (0.42) CYP17A1
SCHEMBL9734674 0.79 CHRM3 (0.42) CYP17A1
SCHEMBL9734678 0.79 CHRM3 (0.42) CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0152031-A2 Azolyl cycloalkanol derivatives and agricultural fungicides SHIONOGI & CO., LTD. (JP) 1985-08-21 EP claimed
US-5091539-A Reacting an ozolyl cycloalkanone with Grignard reagent or alkali metal compound SHIONOGI & CO., LTD. (JP) 1992-02-25 US disclosed
EP-0152031-A2 Azolyl cycloalkanol derivatives and agricultural fungicides SHIONOGI & CO., LTD. (JP) 1985-08-21 EP disclosed