Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 4/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.34 |
| ▸ | IL6ST | P40189 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734677 | 1.00 | SIRT2 (0.35) | SIRT2PRKCADAGLAIL6ST | |
| SCHEMBL28212841 | 0.84 | SIRT2 (0.38) | SIRT2PRKCA | |
| SCHEMBL28212845 | 0.84 | SIRT2 (0.38) | SIRT2PRKCA | |
| SCHEMBL28212843 | 0.84 | SIRT2 (0.38) | SIRT2PRKCA | |
| SCHEMBL16540892 | 0.80 | SIRT2 (0.35) | SIRT2PRKCA | |
| SCHEMBL28213248 | 0.77 | CPT1A (0.43) | SIRT2PRKCA | |
| SCHEMBL7936870 | 0.73 | ELANE (0.34) | PRKCA | |
| SCHEMBL11657987 | 0.72 | SIRT2 (0.37) | SIRT2 | |
| SCHEMBL8163645 | 0.70 | SIRT2 (0.40) | SIRT2PRKCA | |
| SCHEMBL11192405 | 0.69 | SIRT2 (0.37) | SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175186-A | Inhibits pancreas lepase and useful agent in treatment of obesity, hyperlipemia, atherosclerosis and arteriosclerosis | HOFFMANN-LA ROCHE INC. (US) | 1992-12-29 | — | — | US | disclosed |