Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 6/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28212843 | 1.00 | SIRT2 (0.38) | SIRT2PRKCAMMP2MMP9MMP8 | |
| SCHEMBL28212845 | 1.00 | SIRT2 (0.38) | SIRT2PRKCAMMP2MMP9MMP8 | |
| SCHEMBL16540892 | 0.96 | SIRT2 (0.35) | SIRT2PRKCAMMP2MMP9MMP8 | |
| SCHEMBL28213248 | 0.85 | CPT1A (0.43) | SIRT2PRKCAMMP9 | |
| SCHEMBL7936870 | 0.84 | ELANE (0.34) | PRKCA | |
| SCHEMBL9734677 | 0.84 | SIRT2 (0.35) | SIRT2PRKCA | |
| SCHEMBL9734682 | 0.84 | SIRT2 (0.35) | SIRT2PRKCA | |
| SCHEMBL11657987 | 0.78 | SIRT2 (0.37) | SIRT2NAAA | |
| SCHEMBL8163645 | 0.77 | SIRT2 (0.40) | SIRT2PRKCANAAA | |
| SCHEMBL17468384 | 0.76 | MMP2 (0.39) | SIRT2MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107949608-A | Hydrophobic combination | 詹森药业有限公司 | 2018-04-20 | — | — | CN | disclosed |