Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | FABP7 | O15540 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052801 | 1.00 | TSHR (0.60) | TSHRALDH1A1BACE1FABP7FABP5 | |
| SCHEMBL2001189 | 1.00 | TSHR (0.60) | TSHRALDH1A1BACE1FABP7FABP5 | |
| SCHEMBL2001191 | 1.00 | TSHR (0.60) | TSHRALDH1A1BACE1FABP7FABP5 | |
| SCHEMBL14374266 | 1.00 | TSHR (0.60) | TSHRALDH1A1BACE1FABP7FABP5 | |
| SCHEMBL10593392 | 1.00 | TSHR (0.60) | TSHRALDH1A1BACE1FABP7FABP5 | |
| SCHEMBL10593398 | 1.00 | TSHR (0.60) | TSHRALDH1A1BACE1FABP7FABP5 | |
| SCHEMBL4696715 | 1.00 | TSHR (0.60) | TSHRALDH1A1BACE1FABP7FABP5 | |
| SCHEMBL8060653 | 1.00 | TSHR (0.60) | TSHRALDH1A1BACE1FABP7FABP5 | |
| Hydrochloric Acid SCHEMBL1997637 | 0.99 | TSHR (0.62) | TSHRALDH1A1BACE1FABP7FABP5 | |
| Hydrochloric Acid SCHEMBL5473651 | 0.99 | TSHR (0.62) | TSHRALDH1A1BACE1FABP7FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175306-A | Intermediates for hypotensive agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-29 | — | — | US | claimed |
| EP-0115345-B1 | PROCESS FOR THE RESOLUTION OF RACEMIC OPTICALLY ACTIVE BICYCLIC IMINO-ALPHA-CARBOXYLIC ACID ESTERS AND USE OF THE COMPOUNDS OBTAINABLE IN THIS WAY FOR THE SYNTHESIS OF CARBOXYALKYL DIPEPTIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-07 | — | — | EP | claimed |
| US-4659838-A | Method of resolving bicyclic imino-α-carboxylic acid ester racemates | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | disclosed |