Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | FABP7 | O15540 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052801 | 1.00 | TSHR (0.60) | TSHRALDH1A1BACE1FABP7FABP5 | |
| SCHEMBL2001189 | 1.00 | TSHR (0.60) | TSHRALDH1A1BACE1FABP7FABP5 | |
| SCHEMBL2001191 | 1.00 | TSHR (0.60) | TSHRALDH1A1BACE1FABP7FABP5 | |
| SCHEMBL10593392 | 1.00 | TSHR (0.60) | TSHRALDH1A1BACE1FABP7FABP5 | |
| SCHEMBL9734685 | 1.00 | TSHR (0.60) | TSHRALDH1A1BACE1FABP7FABP5 | |
| SCHEMBL10593398 | 1.00 | TSHR (0.60) | TSHRALDH1A1BACE1FABP7FABP5 | |
| SCHEMBL4696715 | 1.00 | TSHR (0.60) | TSHRALDH1A1BACE1FABP7FABP5 | |
| SCHEMBL8060653 | 1.00 | TSHR (0.60) | TSHRALDH1A1BACE1FABP7FABP5 | |
| Hydrochloric Acid SCHEMBL1997637 | 0.99 | TSHR (0.62) | TSHRALDH1A1BACE1FABP7FABP5 | |
| Hydrochloric Acid SCHEMBL5473651 | 0.99 | TSHR (0.62) | TSHRALDH1A1BACE1FABP7FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118561742-A | Rupestonic acid amide derivative containing nitrogen heterocycle, and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2024-08-30 | — | — | CN | claimed |
| CN-118561742-A | Rupestonic acid amide derivative containing nitrogen heterocycle, and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2024-08-30 | — | — | CN | disclosed |
| EP-3154940-B1 | PROCESS FOR THE PREPARATION OF RAMIPRIL | SANOFI AVENTIS DEUTSCHLAND (DE) | 2018-04-18 | — | — | EP | disclosed |
| US-20070232680-A1 | PREPARATION OF RAMIPRIL AND STABLE PHARMACEUTICAL COMPOSITIONS | DR. REDDY'S LABORATORIES, INC. | 2007-10-04 | — | — | US | disclosed |
| US-20070232680-A1 | PREPARATION OF RAMIPRIL AND STABLE PHARMACEUTICAL COMPOSITIONS | DR. REDDY'S LABORATORIES, INC. | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232680-A1 | PREPARATION OF RAMIPRIL AND STABLE PHARMACEUTICAL COMPOSITIONS | REN, ADRA2A, CYP3A5 | TSHR 2870/4885ALDH1A1 647/4885BACE1 1670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.