Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705495 | 0.95 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9036550 | 0.91 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9705108 | 0.91 | ADORA2A (0.35) | AGTR1AGTR2 | |
| SCHEMBL9705028 | 0.90 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9705111 | 0.88 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9734153 | 0.88 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL7680116 | 0.86 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9035862 | 0.86 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9035998 | 0.85 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL7675559 | 0.85 | AGTR1 (0.39) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087634-A | N-substituted imidazol-2-one compounds for treatment of circulatory disorders | G. D. SEARLE & CO. (US) | 1992-02-11 | — | — | US | disclosed |