Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.82 |
| ▸ | NPC1 | O15118 | 6/20 | 0.82 |
| ▸ | RAB9A | P51151 | 6/20 | 0.82 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.82 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.82 |
| ▸ | RELA | Q04206 | 1/20 | 0.82 |
| ▸ | RARB | P10826 | 9/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | RARA | P10276 | 1/20 | 0.69 |
| ▸ | MTOR | P42345 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | STAT3 | P40763 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595854 | 0.92 | SMN1; SMN2 (0.83) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL9723816 | 0.92 | RAB9A (0.97) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL10662853 | 0.92 | RAB9A (0.97) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL9805357 | 0.90 | RAB9A (1.00) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL10557313 | 0.88 | RAB9A (0.71) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL18573222 | 0.86 | RAB9A (0.70) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL9745699 | 0.85 | RARB (0.79) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL11614238 | 0.85 | RARB (0.79) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL11662655 | 0.85 | RARB (0.79) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL9745075 | 0.85 | RARB (0.79) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118442-A | Photochemical stability; low temperature range; rapid response | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1992-06-02 | — | — | US | disclosed |
| EP-0410142-A2 | Optically active liquid crystal compounds | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-01-30 | — | — | EP | disclosed |