SCHEMBL9734748

SCHEMBL9734748

CN(C)CCC(C(=O)O)c1cccc2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 1/20 0.44
CYP2C19 P33261 2/20 0.43
CYP2C9 P11712 1/20 0.43
HPGD P15428 1/20 0.43
HTT P42858 1/20 0.43
SLC6A4 P31645 1/20 0.41
HTR2A P28223 1/20 0.41
HRH1 P35367 1/20 0.41
HTR1B P28222 2/20 0.41
ALDH1A1 P00352 2/20 0.41
ACP3 P15309 1/20 0.40
AOC3 Q16853 1/20 0.40
CTSG P08311 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5638282 0.83 CYP2C9 (0.46) CYP2C19CYP2C9HPGDHTTSLC6A4
SCHEMBL6842064 0.81 ALOX5 (0.44) CYP2C19CYP2C9HPGDHTTSLC6A4
SCHEMBL250818 0.80 CYP2C19 (0.49) CYP2C19CYP2C9HPGDHTTSLC6A4
SCHEMBL447136 0.80 CYP2C9 (0.48) CYP2C19CYP2C9HPGDHTTSLC6A4
SCHEMBL5156697 0.79 KDM4E (0.47) CYP2C19CYP2C9HPGDHTTSLC6A4
SCHEMBL27682003 0.79 CYP2C9 (0.44) CYP2C19CYP2C9HPGDHTTSLC6A4
SCHEMBL18860719 0.78 HTR1B (0.45) UTS2RCYP2C19CYP2C9SLC6A4HTR2A
SCHEMBL8015861 0.78 KDM4E (0.49) CYP2C19CYP2C9HPGDHTT
SCHEMBL2024342 0.78 KDM4E (0.49) CYP2C19CYP2C9HPGDHTT
SCHEMBL1826965 0.78 KDM4E (0.49) CYP2C19CYP2C9HPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5089251-A AROMATIC DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS SANOFI (FR) 1992-02-18 US disclosed
US-4916156-A ANTISEPTIC OR PRESERVATIVES IN PHARMACY, COSMETOLOGY OR FOOD STUFF SANOFI (FR) 1990-04-10 US disclosed