Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734663 | 0.97 | LMNA (0.38) | LMNACYP2C19HIF1A | |
| SCHEMBL9736159 | 0.82 | — | — | |
| SCHEMBL9736417 | 0.80 | LMNA (0.37) | LMNACYP2C19HIF1A | |
| SCHEMBL9736495 | 0.77 | LMNA (0.60) | LMNACYP2C19HIF1A | |
| SCHEMBL11683149 | 0.77 | LMNA (0.40) | LMNACYP2C19HIF1A | |
| Ioversol SCHEMBL24711 | 0.74 | LMNA (0.64) | LMNACYP2C19HIF1A | |
| Ioversol SCHEMBL9745016 | 0.74 | LMNA (0.64) | LMNACYP2C19HIF1A | |
| SCHEMBL9735097 | 0.74 | — | — | |
| SCHEMBL8380649 | 0.72 | CYP2C19 (0.41) | LMNACYP2C19HIF1A | |
| SCHEMBL9739663 | 0.72 | LMNA (0.60) | LMNACYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365541-B1 | PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES | BRACCO S.p.A. (IT) | 1992-08-12 | — | — | EP | disclosed |
| US-5066823-A | Rearrangement reaction, contrast agent for radiology | BRACCO INDUSTRIA CHEMICA S.P.A. (IT) | 1991-11-19 | — | — | US | disclosed |
| EP-0365541-A1 | PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES. | BRACCO IND CHIMICA SPA (IT) | 1990-05-02 | — | — | EP | disclosed |
| WO-1988009328-A1 | PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1988-12-01 | — | — | WO | disclosed |