Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734844 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9ANPC1KDM4ECA1 | |
| Hydrochloric Acid SCHEMBL9736370 | 0.98 | SMN1; SMN2 (0.48) | SMN1; SMN2RAB9ANPC1KDM4ECA1 | |
| Hydrochloric Acid SCHEMBL9736367 | 0.98 | SMN1; SMN2 (0.48) | SMN1; SMN2RAB9ANPC1KDM4ECA1 | |
| SCHEMBL9735084 | 0.82 | CA1 (0.48) | SMN1; SMN2RAB9ANPC1KDM4ECA1 | |
| SCHEMBL9735698 | 0.82 | RAB9A (0.49) | SMN1; SMN2RAB9ANPC1KDM4ECA1 | |
| SCHEMBL9735087 | 0.82 | CA1 (0.48) | SMN1; SMN2RAB9ANPC1KDM4ECA1 | |
| SCHEMBL9735736 | 0.82 | MAPT (0.51) | SMN1; SMN2RAB9ANPC1KDM4ECA1 | |
| SCHEMBL9735705 | 0.82 | RAB9A (0.49) | SMN1; SMN2RAB9ANPC1KDM4ECA1 | |
| SCHEMBL9736486 | 0.82 | NPC1 (0.48) | SMN1; SMN2RAB9ANPC1KDM4ECA1 | |
| SCHEMBL9736491 | 0.82 | NPC1 (0.48) | SMN1; SMN2RAB9ANPC1KDM4ECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112866-A | Sulfonylfluorides as intermediates, also useful in treatment of bone disorders, antisecretory, antiulcer | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |