Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734890 | 1.00 | CYP3A4 (0.33) | CYP3A4HTTSMN1; SMN2SMYD2HDAC3 | |
| SCHEMBL9150618 | 0.90 | HDAC3 (0.33) | CYP3A4HTTSMN1; SMN2SMYD2HDAC3 | |
| SCHEMBL9150610 | 0.90 | HDAC3 (0.33) | CYP3A4HTTSMN1; SMN2SMYD2HDAC3 | |
| SCHEMBL9735826 | 0.89 | SMYD2 (0.31) | CYP3A4HTTSMN1; SMN2SMYD2HDAC3 | |
| SCHEMBL9735823 | 0.89 | SMYD2 (0.31) | CYP3A4HTTSMN1; SMN2SMYD2HDAC3 | |
| SCHEMBL9322456 | 0.85 | SMYD2 (0.33) | CYP3A4HTTSMN1; SMN2SMYD2HDAC1 | |
| SCHEMBL9322461 | 0.85 | SMYD2 (0.33) | CYP3A4HTTSMN1; SMN2SMYD2HDAC1 | |
| SCHEMBL9322465 | 0.85 | SMYD2 (0.33) | CYP3A4HTTSMN1; SMN2SMYD2HDAC1 | |
| SCHEMBL9154359 | 0.85 | TBXAS1 (0.33) | CYP3A4HTTSMN1; SMN2SMYD2HDAC3 | |
| SCHEMBL9154355 | 0.85 | TBXAS1 (0.33) | CYP3A4HTTSMN1; SMN2SMYD2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145861-A | Fluorinated arachidonic acid derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-09-08 | — | — | US | disclosed |
| EP-0315166-A2 | Fluorinated arachidonic acid derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-05-10 | — | — | EP | disclosed |