⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL317175 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL7249488 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL28362750 | 0.96 | NPC1 (0.42) | — | |
| SCHEMBL31220871 | 0.92 | NPC1 (0.40) | — | |
| SCHEMBL28749974 | 0.82 | CA1 (0.35) | — | |
| SCHEMBL5082 | 0.80 | — | — | |
| SCHEMBL6158862 | 0.77 | — | — | |
| SCHEMBL19361934 | 0.76 | — | — | |
| SCHEMBL5228181 | 0.76 | — | — | |
| SCHEMBL6802176 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098917-A | And process for killing fungi | BASF AKTIENGESELLSCHAFT (DE) | 1992-03-24 | — | — | US | claimed |
| US-5028618-A | Imidazole oxirane compounds | BASF AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | claimed |
| EP-0352675-A2 | Substituted imidazolylmethyloxiranes and substituted imidazolylpropenes, their preparation and fungicides containing them | BASF Aktiengesellschaft (DE) | 1990-01-31 | — | — | EP | claimed |
| JP-2088561-A | — | — | None | — | — | JP | disclosed |
| WO-2018132279-A1 | TGF BETA RECEPTOR ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-07-19 | — | — | WO | disclosed |
| WO-2018017633-A1 | TGF Beta RECEPTOR ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-01-25 | — | — | WO | disclosed |
| US-5098917-A | And process for killing fungi | BASF AKTIENGESELLSCHAFT (DE) | 1992-03-24 | — | — | US | disclosed |
| US-5098917-A | And process for killing fungi | BASF AKTIENGESELLSCHAFT (DE) | 1992-03-24 | — | — | US | disclosed |
| US-5028618-A | Imidazole oxirane compounds | BASF AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |
| US-5028618-A | Imidazole oxirane compounds | BASF AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |
| US-5028618-A | Imidazole oxirane compounds | BASF AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |
| EP-0352675-A3 | SUBSTITUTED IMIDAZOLYLMETHYLOXIRANES AND SUBSTITUTED IMIDAZOLYLPROPENES, THEIR PREPARATION AND FUNGICIDES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1990-04-18 | — | — | EP | disclosed |
| EP-0352675-A3 | SUBSTITUTED IMIDAZOLYLMETHYLOXIRANES AND SUBSTITUTED IMIDAZOLYLPROPENES, THEIR PREPARATION AND FUNGICIDES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1990-04-18 | — | — | EP | disclosed |
| JP-H0288561-A | SUBSTITUTED IMIDAZOLYLMETHYLOXIRANE AND SUBSTITUTED IMIDAZOLYLPROPENE AND STERILIZING AGENT CONTAINING THEM | BASF AG | 1990-03-28 | — | — | JP | disclosed |
| EP-0352675-A2 | Substituted imidazolylmethyloxiranes and substituted imidazolylpropenes, their preparation and fungicides containing them | BASF Aktiengesellschaft (DE) | 1990-01-31 | — | — | EP | disclosed |
| EP-0352675-A2 | Substituted imidazolylmethyloxiranes and substituted imidazolylpropenes, their preparation and fungicides containing them | BASF Aktiengesellschaft (DE) | 1990-01-31 | — | — | EP | disclosed |
| EP-0352675-A2 | Substituted imidazolylmethyloxiranes and substituted imidazolylpropenes, their preparation and fungicides containing them | BASF Aktiengesellschaft (DE) | 1990-01-31 | — | — | EP | disclosed |