Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31206499 | 0.71 | MAPT (0.46) | ALDH1A1ALOX15TSHRHSD17B10TP53 | |
| SCHEMBL9305472 | 0.71 | APP (0.46) | ALDH1A1ALOX15TSHRHSD17B10TP53 | |
| SCHEMBL28052526 | 0.71 | PSMB8 (0.33) | TDP1 | |
| SCHEMBL2748327 | 0.69 | PSMB8 (0.36) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL2748587 | 0.69 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL663501 | 0.69 | BACE1 (0.36) | — | |
| SCHEMBL2749435 | 0.69 | PSMB8 (0.56) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL9303940 | 0.69 | ALDH1A1 (0.47) | ALDH1A1ALOX15TSHRHSD17B10TP53 | |
| SCHEMBL9306632 | 0.69 | KMT2A (0.37) | ALDH1A1CYP3A4MEN1KMT2AGAA | |
| SCHEMBL28418261 | 0.68 | MAPT (0.50) | ALDH1A1ALOX15TSHRHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |