SCHEMBL9735194

SCHEMBL9735194

Cc1oc(=O)oc1COC(=O)c1cn(C2CC2)c2cc(N3CC[C@@H](O)C3)c(F)cc2c1=O

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.49
ALDH1A1 P00352 6/20 0.49
HPGD P15428 4/20 0.49
HSD17B10 Q99714 4/20 0.49
LMNA P02545 4/20 0.49
MAPT P10636 1/20 0.49
CYP1A2 P05177 1/20 0.47
TOP2A P11388 1/20 0.47
CYP2C9 P11712 1/20 0.47
TOP2B Q02880 1/20 0.47
PIK3CG P48736 4/20 0.44
PIK3CD O00329 3/20 0.44
PIK3R1 P27986 3/20 0.44
PIK3CA P42336 3/20 0.44
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9735190 1.00 KDM4E (0.49) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL9736237 1.00 KDM4E (0.49) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL9734023 0.87 KDM4E (0.58) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL9734026 0.87 KDM4E (0.58) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL9734430 0.84 ALDH1A1 (0.55) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL9734428 0.84 ALDH1A1 (0.55) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL9735118 0.84 ALDH1A1 (0.55) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL9734106 0.82 KDM4E (0.57) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL9734104 0.82 KDM4E (0.57) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL9735289 0.78 KDM4E (0.72) KDM4EALDH1A1HPGDHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5153204-A Bactericides, animal growth promoters BAYER AKTIENGESELLSCHAFT (DE) 1992-10-06 US disclosed
US-4820716-A ANIMAL GROWTH REGULATORS, BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 1989-04-11 US disclosed