Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025747 | 1.00 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL9025014 | 1.00 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL9457252 | 1.00 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL14418867 | 0.79 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL6014062 | 0.79 | SHBG (0.30) | MEN1KMT2A | |
| SCHEMBL17267078 | 0.79 | SHBG (0.30) | MEN1KMT2A | |
| SCHEMBL12306832 | 0.78 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL8314214 | 0.77 | — | — | |
| SCHEMBL6253583 | 0.77 | — | — | |
| SCHEMBL6253588 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175186-A | Inhibits pancreas lepase and useful agent in treatment of obesity, hyperlipemia, atherosclerosis and arteriosclerosis | HOFFMANN-LA ROCHE INC. (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0185359-B1 | OXETANONE | F. HOFFMANN-LA ROCHE AG (CH) | 1991-12-04 | — | — | EP | disclosed |
| US-4931463-A | PANCREAS LIPASE INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0185359-A2 | Oxetanone | F. HOFFMANN-LA ROCHE AG (CH) | 1986-06-25 | — | — | EP | disclosed |