Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10535978 | 0.85 | TSHR (0.42) | GAACSNK2A1BRAFTSHRSMN1; SMN2 | |
| SCHEMBL9734857 | 0.85 | EGFR (0.36) | NPC1GAACSNK2A1BRAFLMNA | |
| SCHEMBL30902518 | 0.84 | NPC1 (0.53) | NPC1MAOAGAACSNK2A1TSHR | |
| SCHEMBL3277991 | 0.80 | NPC1 (0.61) | NPC1MAOAGAACSNK2A1TSHR | |
| SCHEMBL2229584 | 0.78 | GAA (0.40) | GAACSNK2A1BRAFTSHRCYP3A4 | |
| SCHEMBL12519586 | 0.78 | GAA (0.40) | GAACSNK2A1BRAFTSHRCYP3A4 | |
| SCHEMBL12519780 | 0.78 | GAA (0.40) | GAACSNK2A1BRAFTSHRCYP3A4 | |
| SCHEMBL10424474 | 0.74 | SLC2A1 (0.41) | NPC1MAOAGAACSNK2A1TSHR | |
| SCHEMBL9642579 | 0.74 | SMN1; SMN2 (0.54) | GAATSHRCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL9769730 | 0.72 | NPC1 (0.52) | NPC1MAOAGAACSNK2A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169428-A | Tetrahydrophthalimide derivative and herbicide composition containing same | TOSOH CORPORATION (JP) | 1992-12-08 | — | — | US | disclosed |
| EP-0323271-A1 | Tetrahydrophthalimide derivative and herbicide composition containing the same | Tosoh Corporation (JP) | 1989-07-05 | — | — | EP | disclosed |