Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | ITK | Q08881 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.34 |
| ▸ | FEN1 | P39748 | 4/20 | 0.34 |
| ▸ | PPOX | P50336 | 3/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599131 | 0.86 | SLC2A1 (0.39) | NPC1PPOXCSNK2A1GAA | |
| SCHEMBL9735484 | 0.85 | NPC1 (0.52) | NPC1CSNK2A1GAALMNABRAF | |
| SCHEMBL4678114 | 0.82 | PPOX (0.45) | NPC1ALOX5APFEN1PPOXCSNK2A1 | |
| SCHEMBL9769674 | 0.81 | MAOA (0.36) | NPC1PPOXCSNK2A1GAA | |
| SCHEMBL8879333 | 0.79 | NPC1 (0.43) | NPC1PPOXCSNK2A1GAA | |
| SCHEMBL10535978 | 0.78 | TSHR (0.42) | EGFRITKCSNK2A1GAALMNA | |
| SCHEMBL8602961 | 0.77 | ALDH1A1 (0.47) | PPOXGAAKMT2A | |
| SCHEMBL29278731 | 0.77 | ALDH1A1 (0.47) | PPOXGAAKMT2A | |
| SCHEMBL10811265 | 0.76 | NPC1 (0.38) | NPC1PPOXGAAMEN1LMNA | |
| SCHEMBL8603213 | 0.76 | PPOX (0.56) | NPC1PPOXGAAMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169428-A | Tetrahydrophthalimide derivative and herbicide composition containing same | TOSOH CORPORATION (JP) | 1992-12-08 | — | — | US | disclosed |
| EP-0323271-A1 | Tetrahydrophthalimide derivative and herbicide composition containing the same | Tosoh Corporation (JP) | 1989-07-05 | — | — | EP | disclosed |