SCHEMBL9735776

SCHEMBL9735776

O=C(c1ccc([N+](=O)[O-])cc1)c1c(O)ccc(O)c1C(=O)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 2/20 0.63
LMNA P02545 1/20 0.61
GAA P10253 1/20 0.61
CES1 P23141 2/20 0.61
L3MBTL1 Q9Y468 1/20 0.59
CA1 P00915 3/20 0.59
CA2 P00918 3/20 0.59
TDP1 Q9NUW8 2/20 0.59
MAPK1 P28482 2/20 0.58
POLB P06746 1/20 0.58
ALDH1A1 P00352 2/20 0.57
TSHR P16473 1/20 0.57
CA12 O43570 1/20 0.56
CA9 Q16790 1/20 0.56
CA14 Q9ULX7 1/20 0.56
MAPT P10636 1/20 0.54
CES2 O00748 1/20 0.53
GSK3B P49841 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9735141 0.86 SRD5A2 (0.53) SRD5A2LMNAGAACES1L3MBTL1
SCHEMBL975118 0.85 SRD5A2 (0.83) SRD5A2LMNAGAACES1L3MBTL1
SCHEMBL10723714 0.85 SRD5A2 (0.83) SRD5A2LMNAGAACES1L3MBTL1
SCHEMBL6746532 0.83 TDP1 (0.63) SRD5A2LMNAGAACES1L3MBTL1
SCHEMBL4686670 0.82 SRD5A2 (0.71) SRD5A2LMNAGAACES1L3MBTL1
SCHEMBL28914440 0.79 MAPK1 (0.85) SRD5A2LMNAGAACES1L3MBTL1
SCHEMBL8814597 0.79 GAA (0.67) SRD5A2LMNAGAACES1L3MBTL1
SCHEMBL12490391 0.79 TDP1 (0.77) SRD5A2LMNAGAACES1L3MBTL1
SCHEMBL11269211 0.79 ALDH1A1 (0.58) SRD5A2LMNAGAACES1L3MBTL1
SCHEMBL11141757 0.78 SRD5A2 (0.51) SRD5A2LMNAGAACES1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5086128-A HIGH MOLECULAR WEIGHT ARYLENE SULPHIDE POLYMER MELT MIXED WITH AROMATIC NITRO COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1992-02-04 US disclosed