Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10618087 | 0.88 | MEN1 (0.47) | MEN1KMT2ACYP1A2POLBPDE4B | |
| SCHEMBL582039 | 0.80 | MEN1 (0.52) | MEN1KMT2ACYP1A2POLBPDE4B | |
| SCHEMBL9844294 | 0.79 | MEN1 (0.55) | MEN1KMT2ACYP1A2POLBPDE4B | |
| SCHEMBL11729415 | 0.78 | CYP1A2 (0.41) | MEN1KMT2ACYP1A2POLBPDE4B | |
| SCHEMBL11616177 | 0.75 | L3MBTL1 (0.40) | MEN1KMT2ACYP1A2PDE4BPDE4D | |
| SCHEMBL6342292 | 0.73 | GAA (0.44) | MEN1KMT2ACYP1A2POLBCA1 | |
| SCHEMBL1576984 | 0.73 | MEN1 (0.43) | MEN1KMT2ACYP1A2POLBPDE4B | |
| SCHEMBL1577386 | 0.71 | MEN1 (0.47) | MEN1KMT2ACYP1A2POLBPDE4B | |
| SCHEMBL20202489 | 0.70 | MEN1 (0.45) | MEN1KMT2ACYP1A2POLBPDE4B | |
| SCHEMBL10891276 | 0.70 | MAPT (0.62) | MEN1KMT2ACYP1A2POLBPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091529-A | HERBICIDAL SUBSTITUTED SULPHONYLAMINOAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| US-5021082-A | Pre=and postemergent | BAYER AKTIENGESELLSCHAFT (DE) | 1991-06-04 | — | — | US | disclosed |
| EP-0419831-A2 | Substituted sulfonylaminoazoles | BAYER AG (DE) | 1991-04-03 | — | — | EP | disclosed |
| US-4941912-A | Herbicidal substituted sulphonylaminoazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-17 | — | — | US | disclosed |