Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464454 | 1.00 | LMNA (0.49) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL2171410 | 0.94 | CYP1A2 (0.49) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL28237951 | 0.90 | LMNA (0.46) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL27980667 | 0.86 | LMNA (0.53) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL9123355 | 0.86 | LMNA (0.53) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL9257284 | 0.86 | LMNA (0.53) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL29205221 | 0.85 | CNR2 (0.50) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL28236854 | 0.84 | CYP1A2 (0.46) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL3187650 | 0.82 | PDK2 (0.50) | LMNAMAPTMEN1KMT2AJAK2 | |
| SCHEMBL30396958 | 0.82 | PDK2 (0.50) | LMNAMAPTMEN1KMT2AJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098599-A | Aromatic esters with sulfide groups as liquid crystals | MITSUBISHI RAYON COMPANY LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0354355-A1 | Optically active compound and liquid crystal composition | MITSUBISHI RAYON CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |