SCHEMBL9735884

SCHEMBL9735884

O=C1CC2c3ccccc3CC2N1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.41
HTR2C P28335 2/20 0.41
HTR2B P41595 2/20 0.41
PARP1 P09874 1/20 0.41
TSHR P16473 1/20 0.41
ANPEP P15144 2/20 0.40
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
GRIN3A Q8TCU5 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
CHRNB2 P17787 1/20 0.39
CHRNA4 P43681 1/20 0.39
BRD4 O60885 2/20 0.37
CREBBP Q92793 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21357347 0.86 SRD5A1 (0.49) HTR2AHTR2CHTR2BPARP1TSHR
SCHEMBL1952747 0.84 SRD5A1 (0.54) PARP1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1207971 0.84 SRD5A1 (0.54) PARP1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL9964019 0.84 SRD5A1 (0.54) PARP1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1952744 0.84 SRD5A1 (0.54) PARP1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL21365634 0.77 GRIN2D (0.40) HTR2AHTR2CHTR2BPARP1GRIN2D
SCHEMBL10493527 0.76 PARP1 (0.46) HTR2AHTR2CHTR2BPARP1TSHR
SCHEMBL21357342 0.74 CYP19A1 (0.40) HTR2AHTR2CHTR2BPARP1CREBBP
SCHEMBL21149846 0.72 KMT2A (0.42) TSHRANPEPGRIN2DGRIN3BGRIN1
SCHEMBL9940797 0.72 KMT2A (0.42) TSHRANPEPGRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11039613-B2 Germination promoters SYNGENTA PARTICIPATIONS AG (CH) 2021-06-22 US disclosed
US-11039613-B2 Germination promoters SYNGENTA PARTICIPATIONS AG (CH) 2021-06-22 US disclosed
EP-3580214-B1 GERMINATION PROMOTERS SYNGENTA PARTICIPATIONS AG (CH) 2021-04-07 EP disclosed
EP-3580214-B1 GERMINATION PROMOTERS SYNGENTA PARTICIPATIONS AG (CH) 2021-04-07 EP disclosed
US-20210059251-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-03-04 US disclosed
US-20210059251-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-03-04 US disclosed
WO-2019175025-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2019-09-19 WO disclosed
WO-1992000961-A1 INDANO PYRROLIDINE CARBAMATES PFIZER INC. (US) 1992-01-23 WO disclosed
US-3987183-A TRANSFERASE INHIBITOR, TREATMENT OF MENTAL ABERRATIONS AS SCHIZOPHRENIA MERCK & CO., INC. (US) 1976-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210059251-A1 PLANT GROWTH REGULATOR COMPOUNDS GHITM, GHDC, MST1 HTR2A 3144/4885HTR2C 3528/4885HTR2B 3483/4885
US-11039613-B2 Germination promoters HSF1, CSDE1, CBFB HTR2A 3660/4885HTR2C 3936/4885HTR2B 3902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.