GHDC

GH3 domain-containing protein · Q8N2G8 · GHDC on Sugi Atlas →

0 patent compounds predicted against GHDC, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to GHDC by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Multicentre, Randomised, Open-label, Controlled Study to Evaluate the Effects of Saizen® on Cardiac Function in Growth Hormone Deficient(GHD) Subjects During the Transition Phase From Childhood to Adulthood PHASE4COMPLETED
Low and Conventional Dose of Somatropin in Growth Hormone Deficient Adult Patients PHASE3COMPLETED
Safety and Efficacy Study of MOD-4023 to Treat Children With Growth Hormone Deficiency PHASE3COMPLETED
Cool.Click™ Adolescent Transition Study: Study of Saizen® in Subjects With Childhood-onset Growth Hormone Deficiency PHASE3COMPLETED
A Study to Investigate the Safety and Efficacy of Once-weekly PEG-somatropin (GenSci004) in Children With Growth Hormone Deficiency PHASE3UNKNOWN
Growth Hormone Replacement in Veterans With GWI and AGHD (GWIT) PHASE2RECRUITING
A Study of GenSci134 in Children With Growth Hormone Deficiency (PGHD) PHASE1/PHASE2NOT_YET_RECRUITING
Safety and Efficacy Phase 2 Study of Long-acting hGH (MOD-4023) in Growth Hormone Deficient Children PHASE2COMPLETED
Growth Hormone in a Patient With a Dominant-Negative GHR Mutation PHASE2ACTIVE_NOT_RECRUITING
Follicle-Stimulating Hormone (FSH) and the Onset of Puberty EARLY_PHASE1COMPLETED
Sexually Dimorphic Effects of GHRH in Adult Growth Hormone Testing nanCOMPLETED
Consequence of Lifetime Isolated Growth Hormone Deficiency nanCOMPLETED
Molecular Basis of the Growth Axis in Short Stature nanCOMPLETED
Adipose Tissue and Circulating Markers of Inflammation in GH Deficiency and Changes With GH Therapy nanCOMPLETED
Use of miRNAs in Growth Hormone Deficiency (GHD) nanUNKNOWN
Growth Hormone Feedback to Insulin-like Growth Factor-I (IGF-1) and Oral Glucose Tolerance Test (OGTT) nanCOMPLETED
Chromosome 18 Clinical Research Center nanRECRUITING
Ghrelin and Gastric Emptying in Children With Functional Dyspepsia nanCOMPLETED
Effects of an Amino Acid-Based hGH Secretagogue on Triiodythyronine nanCOMPLETED
304-C03/L3301n: Effects of Growth Hormone on Glucose and Protein Metabolism in Children With Growth Hormone Deficiency nanUNKNOWN
Effects of Growth Hormone Administration on Cardiovascular Risk in Cured Acromegalics With Growth Hormone Deficiency nanCOMPLETED
D3-GHR Polymorphism and Turner Syndrome nanCOMPLETED
Metabolic Studies- Interactions Between GH and Insulin in GHDA nanCOMPLETED
Study of Pituitary Size and Function in Familial Dwarfism of Sindh nanCOMPLETED
miRNA as a Growth Plate Marker After GH nanUNKNOWN
Adipose Tissue and Serum Inflammation in GH Deficiency nanCOMPLETED
Inherited Reproductive Disorders nanRECRUITING
Epidemiology of Insulin Growth Factor (IGF) and Cardiovascular Events nanCOMPLETED
The IGFBP-3 Stimulation Test: A New Tool for the Diagnosis of Growth Hormone Deficiency in Children. nanCOMPLETED
Ketogenic vs. Mediterranean Diet on Metabolic and Hormonal Parameters in Patients With Active Acromegaly nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a GHDC binder may also engage these)

ProteinNameSimilarity
Q99J23 0.997 Q99J23 →
Q643R3 0.976 Q643R3 →
A7MBM2 0.974 A7MBM2 →
D3KCC4 0.973 D3KCC4 →
Q6F5E8 0.972 Q6F5E8 →
Q56A04 0.972 Q56A04 →
Q14296 0.971 Q14296 →
B1WBU5 0.970 B1WBU5 →
Q3UR97 0.970 Q3UR97 →
P52205 0.969 P52205 →
Q5XIH9 0.969 Q5XIH9 →
Q6NUI2 0.969 Q6NUI2 →
Q0V8J4 0.969 Q0V8J4 →
Q99LC9 0.969 Q99LC9 →
Q6NVH7 0.969 Q6NVH7 →
A5YM72 0.969 A5YM72 →
Q561R2 0.968 Q561R2 →
D3ZI76 0.968 D3ZI76 →
P54777 0.968 P54777 →
Q6P5W5 0.968 Q6P5W5 →
Q002B5 0.968 Q002B5 →
TELO2 Telomere length regulation protein TEL2 homolog 0.968 landscape →
POLRMT DNA-directed RNA polymerase, mitochondrial 0.968 landscape →
Q92935 0.967 Q92935 →
Q80XL1 0.967 Q80XL1 →
Q8NCV1 0.967 Q8NCV1 →
P0C5K1 0.967 P0C5K1 →
Q91YD1 0.967 Q91YD1 →
Q9HB75 0.967 Q9HB75 →
Q6PAT0 0.967 Q6PAT0 →