Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.68 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.62 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | ELANE | P08246 | 1/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4811757 | 0.91 | NR4A2 (0.70) | MAOBNR4A1NR4A2NR4A3SRD5A2 | |
| SCHEMBL1068959 | 0.91 | MAOB (0.70) | MAOBNR4A1NR4A2NR4A3SRD5A2 | |
| SCHEMBL6444707 | 0.89 | NR4A2 (0.67) | MAOBNR4A1NR4A2NR4A3SRD5A2 | |
| SCHEMBL8638975 | 0.88 | MAOB (0.63) | MAOBNR4A1NR4A2NR4A3SRD5A2 | |
| SCHEMBL10709793 | 0.88 | KMT2A (0.63) | MAOBSMN1; SMN2ALDH1A1L3MBTL1PARP10 | |
| SCHEMBL28516316 | 0.88 | MAOB (0.68) | MAOBNR4A1NR4A2NR4A3SRD5A2 | |
| SCHEMBL13612596 | 0.88 | MAOB (0.63) | MAOBNR4A1NR4A2NR4A3SRD5A2 | |
| SCHEMBL9185731 | 0.88 | NR4A2 (0.81) | MAOBNR4A1NR4A2NR4A3SRD5A2 | |
| SCHEMBL9574763 | 0.88 | NR4A1 (0.65) | MAOBNR4A1NR4A2NR4A3SRD5A2 | |
| SCHEMBL6199466 | 0.87 | LMNA (0.67) | MAOBNR4A1NR4A2NR4A3SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098599-A | Aromatic esters with sulfide groups as liquid crystals | MITSUBISHI RAYON COMPANY LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0354355-A1 | Optically active compound and liquid crystal composition | MITSUBISHI RAYON CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |