Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735962 | 1.00 | MEN1 (0.50) | MEN1MAPTKMT2ALMNACYP1A2 | |
| SCHEMBL9735955 | 1.00 | MEN1 (0.50) | MEN1MAPTKMT2ALMNACYP1A2 | |
| SCHEMBL8133010 | 0.94 | MEN1 (0.48) | MEN1MAPTKMT2ALMNACYP1A2 | |
| SCHEMBL8133007 | 0.94 | MEN1 (0.48) | MEN1MAPTKMT2ALMNACYP1A2 | |
| SCHEMBL3921874 | 0.84 | MAPT (0.67) | MEN1MAPTKMT2ALMNACYP1A2 | |
| SCHEMBL8876005 | 0.81 | MEN1 (0.44) | MEN1MAPTKMT2ALMNACYP1A2 | |
| SCHEMBL8876007 | 0.81 | MEN1 (0.44) | MEN1MAPTKMT2ALMNACYP1A2 | |
| SCHEMBL13939604 | 0.80 | MAPT (0.57) | MEN1MAPTKMT2ALMNACYP1A2 | |
| SCHEMBL2572526 | 0.80 | MAPT (0.57) | MEN1MAPTKMT2ALMNACYP1A2 | |
| SCHEMBL15573909 | 0.79 | MEN1 (0.46) | MEN1MAPTKMT2ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145959-A | Enzyme inhibitors; antilipemic agents; treatment of atherosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |
| US-5075311-A | Anticholesterol agents | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-24 | — | — | US | disclosed |