Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8133007 | 1.00 | MEN1 (0.48) | MEN1LMNACYP1A2MAPTCYP2C9 | |
| SCHEMBL9735963 | 0.94 | MEN1 (0.50) | MEN1LMNACYP1A2MAPTCYP2C9 | |
| SCHEMBL9735955 | 0.94 | MEN1 (0.50) | MEN1LMNACYP1A2MAPTCYP2C9 | |
| SCHEMBL9735962 | 0.94 | MEN1 (0.50) | MEN1LMNACYP1A2MAPTCYP2C9 | |
| SCHEMBL15573909 | 0.86 | MEN1 (0.46) | MEN1LMNAMAPTKMT2ANPSR1 | |
| SCHEMBL18060097 | 0.86 | MEN1 (0.46) | MEN1LMNAMAPTKMT2ANPSR1 | |
| SCHEMBL3921874 | 0.82 | MAPT (0.67) | MEN1LMNACYP1A2MAPTCYP2C9 | |
| SCHEMBL8005684 | 0.78 | RAB9A (0.37) | MEN1LMNACYP1A2MAPTCYP2C9 | |
| SCHEMBL13939604 | 0.77 | MAPT (0.57) | MEN1LMNACYP1A2MAPTCYP2C9 | |
| SCHEMBL2572526 | 0.77 | MAPT (0.57) | MEN1LMNACYP1A2MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121330-A | CARDIOVASCULAR DISORDERS; ANTICHOLESTEROL AGENTS; ANTILIPEMIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |