Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA3 | P07451 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzofuran SCHEMBL27880879 | 0.98 | MAOA (0.40) | MAOAMAOBFTODYRK1ACDK9 | |
| Benzofuran SCHEMBL29415475 | 0.92 | — | — | |
| Benzofuran SCHEMBL29393518 | 0.92 | — | — | |
| Benzofuran SCHEMBL3160534 | 0.92 | — | — | |
| Benzofuran SCHEMBL5564 | 0.92 | — | — | |
| Benzofuran SCHEMBL5834531 | 0.92 | MAOA (0.46) | MAOAMAOBFTODYRK1ACDK9 | |
| Benzofuran SCHEMBL28153539 | 0.90 | MAOA (0.41) | MAOAMAOBFTODYRK1ACA12 | |
| Benzofuran SCHEMBL11251534 | 0.90 | MAOA (0.44) | MAOAMAOBFTODYRK1ACDK9 | |
| Benzofuran SCHEMBL118311 | 0.90 | CYP2A6 (0.45) | MAOAMAOBFTODYRK1ACDK9 | |
| Benzofuran SCHEMBL1129070 | 0.90 | MAOA (0.44) | MAOAMAOBFTODYRK1ACDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134140-A | Psychotropic benzofuran derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-07-28 | — | — | US | disclosed |