Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 5/20 | 0.65 |
| ▸ | ANPEP | P15144 | 8/20 | 0.54 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27305210 | 0.98 | LAP3 (0.67) | LAP3ANPEPERAP2LMNACYP3A4 | |
| SCHEMBL3029102 | 0.98 | LAP3 (0.67) | LAP3ANPEPERAP2LMNACYP3A4 | |
| SCHEMBL11359987 | 0.93 | LAP3 (0.61) | LAP3ANPEPERAP2LMNACYP3A4 | |
| Guanidine SCHEMBL28573373 | 0.92 | LAP3 (0.57) | LAP3ANPEPERAP2LMNACYP3A4 | |
| SCHEMBL12994398 | 0.85 | LAP3 (0.70) | LAP3ANPEPERAP2ERAP1METAP1 | |
| SCHEMBL27993032 | 0.82 | — | — | |
| SCHEMBL3947666 | 0.81 | LAP3 (0.65) | LAP3ANPEPERAP2LMNACYP3A4 | |
| SCHEMBL10487202 | 0.79 | LAP3 (0.67) | LAP3ANPEPLMNACYP3A4NFKB1 | |
| Ammonia Solution, Strong SCHEMBL5015567 | 0.79 | LAP3 (0.63) | LAP3ANPEPERAP2LMNACYP3A4 | |
| SCHEMBL7814294 | 0.79 | LAP3 (1.00) | LAP3ANPEPERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976762-A | RADIOACTIVE DRUGS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1976-08-24 | — | — | US | claimed |
| US-5155227-A | Compounds for site-enhanced delivery of radionuclides | UNIVERSITY OF FLORIDA (US) | 1992-10-13 | — | — | US | disclosed |
| US-4963688-A | Compounds for site-enhanced delivery of radionuclides and uses thereof | UNIVERSITY OF FLORIDA (US) | 1990-10-16 | — | — | US | disclosed |
| EP-0187832-A1 | COMPOUNDS FOR SITE-ENHANCED DELIVERY OF RADIONUCLIDES AND USES THEREOF | UNIVERSITY OF FLORIDA (US) | 1986-07-23 | — | — | EP | disclosed |
| WO-1986000898-A1 | COMPOUNDS FOR SITE-ENHANCED DELIVERY OF RADIONUCLIDES AND USES THEREOF | UNIVERSITY OF FLORIDA (US) | 1986-02-13 | — | — | WO | disclosed |
| US-3976762-A | RADIOACTIVE DRUGS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1976-08-24 | — | — | US | disclosed |