Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ARG1 | P05089 | 1/20 | 0.41 |
| ▸ | ARG2 | P78540 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16781446 | 1.00 | SMN1; SMN2 (0.57) | SMN1; SMN2HIF1AMMP8FDPSCYP1A2 | |
| SCHEMBL3805248 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2HIF1AMMP8FDPSCYP1A2 | |
| Lithium SCHEMBL8632590 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2HIF1AMMP8FDPSCYP1A2 | |
| SCHEMBL7939924 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1AMMP8FDPSCYP1A2 | |
| SCHEMBL26854 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2HIF1AMMP8FDPSCYP1A2 | |
| SCHEMBL28125890 | 0.79 | HIF1A (0.55) | SMN1; SMN2HIF1AMMP8FDPSCYP1A2 | |
| SCHEMBL10483829 | 0.79 | HIF1A (0.55) | SMN1; SMN2HIF1AMMP8FDPSCYP1A2 | |
| SCHEMBL15775881 | 0.79 | MMP8 (0.72) | SMN1; SMN2HIF1AMMP8CYP1A2CYP2C9 | |
| SCHEMBL14873849 | 0.78 | MMP8 (0.55) | SMN1; SMN2HIF1AMMP8TAAR1MAPT | |
| SCHEMBL10500960 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2HIF1AFDPSCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144077-A | PROCESS FOR WORKING UP THE CRYSTALLIZATION MOTHER LIQUOR FROM THE RESOLUTION OF THE RACEMATE OF 1-(4-CHLOROPHENYL)-ETHYLAMINE | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-01 | — | — | US | disclosed |