SCHEMBL9736313

SCHEMBL9736313

C=C1N(C)c2ccc(OCCCCCCCC)cc2C1(C)C

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.42
LTA4H P09960 1/20 0.42
NR5A1 Q13285 1/20 0.41
TSHR P16473 2/20 0.40
TP53 P04637 2/20 0.39
NPC1 O15118 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9734981 0.96 PDK2 (0.39) PDK2LTA4H
SCHEMBL9750240 0.85 MEN1 (0.40) PDK2TSHRTP53NPC1HPGD
SCHEMBL10881205 0.84 PDK2 (0.39) PDK2TSHRHPGD
SCHEMBL26022329 0.82 PDK2 (0.42) PDK2TSHRTP53
SCHEMBL9735859 0.78 ESR1 (0.38) TP53
SCHEMBL3819871 0.77 MAPT (0.43) HPGD
SCHEMBL5850674 0.77 MPI (0.37) TP53
SCHEMBL26024106 0.74 POLB (0.44)
SCHEMBL6474703 0.72 HSPA9 (0.42)
SCHEMBL9750440 0.72 GRIA2 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5130442-A Compounds for forming color in recording material based on acid developers BAYER AKTIENGESELLSCHAFT (DE) 1992-07-14 US disclosed
EP-0431425-A2 Chromogen enamine compounds, their preparation and use as colour formers BAYER AG (DE) 1991-06-12 EP disclosed