Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736997 | 0.87 | CA2 (0.44) | KDM4ECA2ALDH1A1HPGDUSP2 | |
| SCHEMBL9736371 | 0.84 | PTGES2 (0.44) | KDM4ECA2ALDH1A1HPGDUSP2 | |
| SCHEMBL9737123 | 0.82 | CA2 (0.45) | KDM4ECA2ALDH1A1HPGDUSP2 | |
| SCHEMBL11192732 | 0.80 | KDM4E (0.59) | KDM4ECA2ALDH1A1HPGDUSP2 | |
| SCHEMBL11165688 | 0.80 | CISD1 (0.49) | KDM4ECA2ALDH1A1HPGDUSP2 | |
| SCHEMBL11165513 | 0.79 | CISD1 (0.42) | KDM4ECA2ALDH1A1HPGDUSP2 | |
| SCHEMBL9737268 | 0.79 | CA2 (0.66) | KDM4ECA2ALDH1A1HPGDUSP2 | |
| SCHEMBL9739881 | 0.78 | SCN1A (0.40) | KDM4ECA2ALDH1A1CA9 | |
| SCHEMBL11159696 | 0.78 | CISD1 (0.58) | KDM4ECA2ALDH1A1HPGDUSP2 | |
| SCHEMBL11194787 | 0.77 | KDM4E (0.46) | KDM4ECA2ALDH1A1HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145867-A | NAPHTHYLALKYLAMINO-SUBSTITUTED SULFAMOYLBENZOIC ACID DERIVATIVES, AND THE USE THEREOF AS MEDICINES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |