Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9100229 | 0.82 | MAPT (0.59) | MAPTMEN1KMT2ARAB9ACA1 | |
| SCHEMBL10341647 | 0.82 | RPS6KA2 (0.43) | MAPTMEN1KMT2ACA1CA2 | |
| SCHEMBL10341662 | 0.80 | CA1 (0.44) | MAPTMEN1KMT2ARAB9ACA1 | |
| Hydrochloric Acid SCHEMBL9736836 | 0.80 | RPS6KA2 (0.42) | MAPTMEN1KMT2ACA1CA2 | |
| SCHEMBL4418270 | 0.80 | CA1 (0.44) | MAPTMEN1KMT2ACA1CA2 | |
| Hydrochloric Acid SCHEMBL9734655 | 0.79 | HPGD (0.46) | MAPTMEN1KMT2ACA1CA2 | |
| SCHEMBL4410568 | 0.79 | GAA (0.66) | MAPTMEN1KMT2ARAB9ACA1 | |
| SCHEMBL4411321 | 0.79 | ALDH1A1 (0.54) | MAPTMEN1KMT2ACA1CA2 | |
| Hydrochloric Acid SCHEMBL9735996 | 0.78 | GAA (0.63) | MAPTMEN1KMT2ARAB9ACA1 | |
| SCHEMBL15044746 | 0.78 | MAPT (0.53) | MAPTMEN1KMT2ARAB9ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358438-A2 | Ethanesulfonamide derivatives | ORTHO PHARMACEUTICAL CORPORATION (US) | 1990-03-14 | — | — | EP | claimed |
| US-5112866-A | Sulfonylfluorides as intermediates, also useful in treatment of bone disorders, antisecretory, antiulcer | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0358438-A2 | Ethanesulfonamide derivatives | ORTHO PHARMACEUTICAL CORPORATION (US) | 1990-03-14 | — | — | EP | disclosed |