Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736440 | 1.00 | TSHR (0.47) | TSHRSMN1; SMN2KDM4ETDP1L3MBTL1 | |
| SCHEMBL9736438 | 1.00 | TSHR (0.47) | TSHRSMN1; SMN2KDM4ETDP1L3MBTL1 | |
| SCHEMBL2808184 | 0.83 | ALDH1A1 (0.45) | TSHRSMN1; SMN2KDM4ETDP1L3MBTL1 | |
| SCHEMBL12851372 | 0.83 | ALDH1A1 (0.45) | TSHRSMN1; SMN2KDM4ETDP1L3MBTL1 | |
| SCHEMBL2808186 | 0.83 | ALDH1A1 (0.45) | TSHRSMN1; SMN2KDM4ETDP1L3MBTL1 | |
| SCHEMBL2048794 | 0.81 | TSHR (0.54) | TSHRSMN1; SMN2KDM4ETDP1L3MBTL1 | |
| SCHEMBL7807838 | 0.81 | TSHR (0.54) | TSHRSMN1; SMN2KDM4ETDP1L3MBTL1 | |
| SCHEMBL4013088 | 0.81 | TSHR (0.54) | TSHRSMN1; SMN2KDM4ETDP1L3MBTL1 | |
| SCHEMBL9738478 | 0.79 | TSHR (0.52) | TSHRSMN1; SMN2KDM4ETDP1L3MBTL1 | |
| SCHEMBL9738473 | 0.79 | TSHR (0.52) | TSHRSMN1; SMN2KDM4ETDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145954-A | Fungicides, insecticides, plant growth regualtors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-09-08 | — | — | US | disclosed |
| EP-0244077-A1 | Sulphides derived from substituted phenyl-2-acrylic acid | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-11-04 | — | — | EP | disclosed |