SCHEMBL973650

SCHEMBL973650

NCCC12CC3CC(CC(C3)C1)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 6/20 1.00
GRIN3B O60391 6/20 1.00
GRIN1 Q05586 6/20 1.00
GRIN2A Q12879 6/20 1.00
GRIN2B Q13224 6/20 1.00
GRIN2C Q14957 6/20 1.00
GRIN3A Q8TCU5 6/20 1.00
ALDH1A1 P00352 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
TSHR P16473 2/20 0.41
LMNA P02545 2/20 0.41
SLC22A2 O15244 1/20 0.41
SLC22A1 O15245 1/20 0.41
NFKB1 P19838 1/20 0.41
STAT6 P42226 1/20 0.41
SLC47A1 Q96FL8 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
EPHX2 P34913 4/20 0.41
CA12 O43570 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1677777 0.97 GRIN2D (0.95) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1758707 0.84 GRIN2D (1.00) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL3790792 0.84 GRIN2D (0.73) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Hydrochloric Acid SCHEMBL1758966 0.82 GRIN2D (0.95) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL10704716 0.82 GRIN2D (1.00) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL11697939 0.82 GRIN2D (0.68) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1149893 0.80 GRIN2D (0.95) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL15373738 0.78 GRIN2D (0.64) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL10735027 0.77 GRIN2D (0.61) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL10957944 0.77 GRIN2D (0.76) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120131975-A Host-guest fucoidin carrier, preparation method and application thereof, fucoidin nanocrystalline delivery system, preparation method and application thereof, pharmaceutical composition and application thereof 石河子大学第一附属医院 2025-06-13 CN claimed
CN-119752061-A Antibacterial, antistatic and flame-retardant polystyrene composite material and preparation method thereof 宋树屏 2025-04-04 CN claimed
CN-111470835-A Method and process for repairing concrete cracks in road and bridge construction 杭州市城市建设基础工程有限公司 2020-07-31 CN claimed
US-20120190680-A1 Heteroaryl Amide Analogues H. LUNDBECK A/S (DK) 2012-07-26 US claimed
EP-2185560-A1 HETEROARYL AMIDE ANALOGUES H. Lundbeck A/S (DK) 2010-05-19 EP claimed
WO-2009023623-A1 HETEROARYL AMIDE ANALOGUES H, LUNDBECK A/S (DK) 2009-02-19 WO claimed
EP-0561863-B1 AMIDIC DERIVATIVES OF GLUTAMIC, ASPARTIC AND 2-AMINO ADIPIC ACIDS WITH ANTIGASTRIN ACTIVITY ROTTA RESEARCH LAB (IT) 1994-11-02 EP claimed
EP-0561863-A1 AMIDIC DERIVATIVES OF GLUTAMIC, ASPARTIC AND 2-AMINO ADIPIC ACIDS WITH ANTIGASTRIN ACTIVITY. ROTTA RESEARCH LAB (IT) 1993-09-29 EP claimed
WO-1992010479-A1 AMIDIC DERIVATIVES OF GLUTAMIC, ASPARTIC AND 2-AMINO ADIPIC ACIDS WITH ANTIGASTRIN ACTIVITY ROTTA RESEARCH LABORATORIUM S.P.A. (IT) 1992-06-25 WO claimed
US-20260092039-A1 DUAL INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE UNIV BARCELONA (ES) 2026-04-02 US disclosed
EP-4676916-A1 DUAL INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE Universitat De Barcelona (ES) 2026-01-14 EP disclosed
EP-4598964-A2 ANTI-IGE ANTIBODIES Abwiz Bio, Inc. (US) 2025-08-13 EP disclosed
CN-120131975-A Host-guest fucoidin carrier, preparation method and application thereof, fucoidin nanocrystalline delivery system, preparation method and application thereof, pharmaceutical composition and application thereof 石河子大学第一附属医院 2025-06-13 CN disclosed
CN-119752061-A Antibacterial, antistatic and flame-retardant polystyrene composite material and preparation method thereof 宋树屏 2025-04-04 CN disclosed
US-4289773-A ETHYL 6,7-DIBROMO-3,4-DIHYDRO-3-OXOQUINOXALINE CARBOXYLATE AND A HINDERED AMINE ELI LILLY AND COMPANY (US) 1981-09-15 US disclosed
EP-0029658-A1 Salts of dihalo-2-quinoxaline carboxylic acids, their preparation and pharmaceutical formulations containing them ELI LILLY AND COMPANY (US) 1981-06-03 EP disclosed
US-4271162-A ETHYL 6,7-DICHLORO-3,4-DIHYDRO-3-ONOQUINOXALINE CARBOXYLATE AND 1-AMINOADAMANTANE ELI LILLY AND COMPANY (US) 1981-06-02 US disclosed
US-4100170-A ANTIHYPERTENSIVE AGENTS, MONOAMINE OXIDASE INHIBITORS PENNWALT CORPORATION (US) 1978-07-11 US disclosed
US-4064135-A Certain thiazole-5-carboxamide compounds SYNTEX (U.S.A.) INC. (US) 1977-12-20 US disclosed
US-4064258-A Thiazole cardiovascular agents SYNTEX (U.S.A.) INC. (US) 1977-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092039-A1 DUAL INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE BACE2, BACE1, GLS2 GRIN2D 63/4885GRIN3B 128/4885GRIN1 31/4885
US-20120190680-A1 Heteroaryl Amide Analogues P2RX3, P2RX2, ADORA2A GRIN2D 182/4885GRIN3B 136/4885GRIN1 221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.