Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 13/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735746 | 0.78 | HPGD (0.50) | NPC1RAB9AALDH1A1CA12CA1 | |
| SCHEMBL2089558 | 0.77 | NPC1 (0.59) | NPC1RAB9AGAAFAAHTSHR | |
| SCHEMBL2200288 | 0.76 | NPC1 (0.58) | NPC1RAB9AFAAHTSHR | |
| SCHEMBL19946498 | 0.76 | NPC1 (0.58) | NPC1RAB9AFAAHTSHR | |
| SCHEMBL2089958 | 0.76 | NPC1 (0.58) | NPC1RAB9AFAAHTSHR | |
| SCHEMBL7929814 | 0.76 | NPC1 (0.58) | NPC1RAB9AFAAHTSHR | |
| SCHEMBL5948127 | 0.76 | NPC1 (0.58) | NPC1RAB9AFAAHTSHR | |
| SCHEMBL7930488 | 0.76 | NPC1 (0.58) | NPC1RAB9AFAAHTSHR | |
| SCHEMBL8957605 | 0.76 | NPC1 (0.58) | NPC1RAB9AFAAHTSHR | |
| SCHEMBL19946505 | 0.76 | NPC1 (0.58) | NPC1RAB9AFAAHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112866-A | Sulfonylfluorides as intermediates, also useful in treatment of bone disorders, antisecretory, antiulcer | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |