Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735749 | 1.00 | HPGD (0.50) | HPGDFFAR1FFAR4ALDH1A1CRHBP | |
| Hydrochloric Acid SCHEMBL9736717 | 0.98 | HPGD (0.49) | HPGDFFAR1FFAR4ALDH1A1CRHBP | |
| Hydrochloric Acid SCHEMBL9736714 | 0.98 | HPGD (0.49) | HPGDFFAR1FFAR4ALDH1A1CRHBP | |
| Hydrochloric Acid SCHEMBL9736538 | 0.83 | HPGD (0.44) | HPGDFFAR4ALDH1A1HTTCA2 | |
| SCHEMBL9736679 | 0.78 | NPC1 (0.57) | ALDH1A1CA2CA12CA1CA9 | |
| SCHEMBL5518347 | 0.75 | HPGD (0.51) | HPGDFFAR1FFAR4ALDH1A1CRHBP | |
| SCHEMBL9735736 | 0.75 | MAPT (0.51) | HPGDALDH1A1NPSR1CA2SMN1; SMN2 | |
| SCHEMBL9734847 | 0.73 | SMN1; SMN2 (0.49) | HPGDALDH1A1HTTCA2SMN1; SMN2 | |
| SCHEMBL11783560 | 0.73 | HPGD (0.50) | HPGDFFAR1FFAR4ALDH1A1CRHBP | |
| SCHEMBL10341623 | 0.72 | HPGD (0.53) | HPGDFFAR1FFAR4ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112866-A | Sulfonylfluorides as intermediates, also useful in treatment of bone disorders, antisecretory, antiulcer | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |